MHM Magazine

Presentation of Alzheimer’s Disease (Stahl) Progression of Alzheimer’s Disease PREVENTION & SLOWING DOWN ONSET OF ALZHEIMER’S DISEASE The South African Society of Psychiatrists (SASOP) guidelines, 2012, there are a number of factors that can slow down the onset of Alzheimer’s Disease. Medical treatments include Hormone Replacement Therapy (oestrogen), anti- inflammatories, Apolipoprotein E2 or E3, supplementation with Vitamins B, C, D and Calcium with or without NSAIDs, and control of cardiovascular risk factors. Lifestyle factors include red wine (resveratrol), intellectual stimulation, healthy eating, coffee, chocolate, as well as sleep and exercise. The Cache County Study (Norton et al, JAGS, 2010) found that spouses of patients with dementia have a 6 times greater risk of dementia themselves. Husbands of women with dementia have an even greater risk – they are 12 times more likely to develop dementia. In conclusion, ageing involves a gradual decline in our physiological and physical abilities. Up to 30% of elderly patients will suffer Mild Cognitive Impairment (MCI). Patients with MCI show a modest decline in cognition, behaviour and function, and their social and occupational abilities are disrupted. MCI marks a transition between normal ageing and dementia and, therefore, is an ideal time to recognise, prevent or delay the onset on dementia. As in many areas, the earlier treatment begins, the better the prognosis is. References available upon request Issue 3 | 2021 | MENTALHEALTHMATTERS | 39 MHM