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South Africa’s leading amitriptyline 2 References: 1. LEUCHT C, HUHN M, LEUCHT S. 2012. Amitriptyline versus placebo for major depressive disorder (Review). Cochrane Database of Systematic Reviews , Issue 12. Art. No.: CD009138. DOI: 10.1002/14651858.CD009138.pub2 . 2. IMS data July 2021 S5 TREPILINE 10. Reg. No.: J/1.2/219. Each tablet contains 10 mg amitriptyline hydrochloride. S5 TREPILINE 25. Reg. No.: J/1.2/220. Each tablet contains 25 mg amitriptyline hydrochloride. For full prescribing information refer to the professional information approved by the medicines regulatory authority (07/2017). Trademarks are owned by or licensed to the Aspen Group of companies. © 2021 Aspen Group of companies or its licensor. All rights reserved. Marketed by Aspen Pharmacare for Pharmacare Limited. Co. Reg. No.: 1898/000252/06. Healthcare Park, Woodlands Drive, Woodmead, 2191. ZAR-AMI-08-21-00001 09/2021 The TREPILINE Tri-Factor TRUST THROUGH THE DECADES 1980 1990 2000 2010 2020 South Africa’s leading amitriptyline 2 References: 1. LEUCHT C, HUHN M, LEUCHT S. 012. Amitriptyline versus placebo for major depressive disorder (Review). Cochrane Dat base of Systematic Reviews , Issue 12. Art. No.: CD009138. DOI: 10.1002/14651858.CD009138.pub . 2. IMS data July 2021 S5 TREPILINE 10. Reg. No.: J/1.2/219. Each t blet contains 10 mg amitriptyline hydrochloride. S5 TREPILINE 25. Reg. N .: J/1.2/220. Each tablet contains 25 mg amitriptyline hydrochloride. For full prescribing information refer to the professional information approved by the medicines regulatory authority (07/2017). Trademarks are owned by or licensed to the Aspen Group of companies. © 2021 Aspen Group of companies or its licensor. All rights reserved. Marketed by Aspen Pharmacare for Pharmacare Limited. Co. Reg. No.: 1898/000252/06. Healthcare Park, Woodlands Drive, Woodmead, 2191. ZAR-AMI-08-21-00001 09/2021 The TREPILINE ri-Factor TRUST THROUGH THE DECADES 1980 1990 2000 2010 2020 South Africa’s l i itri tyli 2 R ferences: 1. LEUCHT C, HUHN M, LEUCHT S. 2012. Amitriptyline ersus plac bo for maj r depr ssive disorder (Review). Cochrane Database of Systematic Reviews , Is e 12. Art. N .: CD009138. DOI: 10.1002/14651858.CD009138.pub2 . 2. IMS da July 2021 S5 TREPILINE 10. eg. o.: J/1.2/219. Each ta let contains 10 mg amitriptyline hydrochloride. S5 TREPILINE 25. Reg. No.: J/1.2/220. Each tablet contains 25 mg amitriptyline hydrochloride. For full prescribing information refer to the professional information approved by the medicines regulatory authority (07/2017). Trademarks are wned by or licensed to the Aspen Group of companies. © 2021 Aspen Group of companies or its licensor. All rights reserved. Market d by Aspen Pharmacare for Pharmacare Limited. Co. Reg. No.: 898/000252/ 6. Healthcare Park, Woodlands Drive, Woodmead, 2191. ZAR-AMI-08-21-00001 09/2021 I I ri- t r T T THROUGH THE DECADES 1980 1990 2 00 2010 2020

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