MHM Magazine

Product Name Active Ingredient Strength Schedule Pack Size Dosage Form Item Code NAPPI Code Barcode SEP (Incl. VAT) Bupropion XR 150 ADCO Bupropion 150 mg S5 28 and 30 Extended release tablets 213007 3003761001 6004406007353 R194.06 Customer Care 011 635 0000 customercare@adcock.com Brand Manager 011 635 0680 Samantha.Loveday@adcock.com Orders Department 011 635 1050 Pharma.orders@adcock.com For further information, please contact: Introducing NEW Bupropion XR 150 ADCO Dear Healthcare Professional Adcock Ingram Generics is proud to announce the availability of Bupropion XR 150 ADCO , a distinctly different antidepressant addition to the existing drug range. 1,2 Bupropion XR 150 ADCO is a distinctive neuropharmacological agent indicated for major depressive disorder, with dual action * on noradrenaline and dopamine neurotransmission (NDRI) and comparable antidepressant effects to current treatment regimes. 2,3 NDRI - Noradrenaline and dopamine re-uptake inhibitor; *Dual action refers to inhibition of neuronal noradrenaline and dopamine re-uptake in the synaptic cleft; 2 # Therapeutic advantage is gained by dual action on noradrenaline and dopamine neurotransmission causing enhanced monoaminergic effects and a reduction in the noradrenergic symptom cluster (decreased positive effect) which include loss of energy and fatigue, loss of self-care and motivation and decreased concentration. 4 References: 1 . Bupropion XR 150 ADCO Professional Information Leaflet. January 2021. 2 . Stahl SM, Pradko JF, Haight BR, et al . A Review of the Neuropharmacology of Bupropion, a Dual Norepinephrine and Dopamine Reuptake Inhibitor. Prim Care Companion J Clin Psychiatry 2004;6(4):159-166. 3 . Fava M, Rush AJ, Thase ME, et al . 15 Years of Clinical Experience With Bupropion HCl: From Bupropion to Bupropion SR to Bupropion XL. Prim Care Companion J Clin Psychiatry 2005;(3):106-113. 4 . Bupropion. Medline Plus Information. Available at: https://medlineplus.gov/druginfo/meds/a695033.html. Last accessed: August 2021. 5 . Generics Dictionary [online]. Available at: http://www.generic.co.za/frontend/ generics?utf8=%E2%9C%93&q%5Bactive_ingredient_name_eq%5D=BUPROPION. [Accessed 30 August 2021]. For full prescribing information please refer to the professional information approved by SAHPRA (South African Health Products Regulatory Authority). S5 Bupropion XR 150 Adco. Each extended-release tablet contains bupropion hydrochloride 150 mg. Reg. No.: 50/1.2/0967.965. Adcock Ingram Limited. Reg. No.: 1949/034385/06. 1 New Road, Midrand, 1685. Private Bag X69, Bryanston, 2021. Tel.: +27 11 635 0000. www.adcock.com 2021090710150888. Bupropion XR 150 ADCO offers a therapeutic advantage over serotonergic antidepressants in the treatment of depressive symptoms of decreased positive affect. #2,4 It offers once daily dosing and a monthly cost saving of 58 % vs. originator. 1,5 Live Today. Brighter Tomorrow. 1 NEW Cingulate 16108