SAGES Magazine

THE SOUTH AFRICAN GASTROENTEROLOGY REVIEW 2021 | VOLUME 19 | ISSUE 2 | 37 References: 1. Calabrese C, Fabbri A, Di Febo G. Long-term management of GERD in the elderly with pantoprazole. Clin Interventions Aging 2007; 2 (1):85-92. 2. PENTOZ ® approved package insert. Dr. Reddy’s Laboratories (Pty) Limited. 19 March 2010. 3. Choi YJ, Kim N, Jang IJ, Cho JY, et al. Pantoprazole Does Not Reduce the Antiplatelet Effect of Clopidogrel: A Randomized Controlled Trial in Korea. Gut and Liver 2017; 11 (4):1-8. Pentoz 20. Reg. No.: 41/11.4.3/0641. Each film-coated tablet contains pantoprazole sodium sesquihydrate equivalent to pantoprazole 20 mg. Pentoz 40. Reg. No.: 41/11.4.3/0642. Each film-coated tablet contains pantoprazole sodium sesquihydrate equivalent to pantoprazole 40 mg. Dr. Reddy’s Laboratories (Pty) Ltd. Reg. No. 2002/014163/07. Block B, 204 Rivonia Road, Morningside, Sandton 2057. Tel: +27 11 324 2100, www.drreddys. co.za. For full prescribing information refer to package insert approved by the medicines regulatory authority. ZA/02/2020-2022/PENTOZ/001. 38087 03/20 In the pursuit of perfection... pantoprazole is packed with potential 1 Efficacy is independent of the patient’s age 1 Reduced risk of drug-drug interactions due to a lower affinity for cytochrome P450 system 1 Symptomatic improvement (e.g. heartburn, acid regurgitation, pain on swallowing) 2 No dosage adjustments required in elderly or with renal impairment 1,2 Long-term management and prevention of relapse in gastro-oesophageal reflux disease (GORD) 2 Does not increase platelet aggregation in patients receiving dual antiplatelet therapy 3

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