SAGES Magazine

DIFFERENT PEOPLE, DIFFERENT CHOICES. S3 PENTASA ® SACHETS 2 g. Each sachet contains 2 g mesalazine. Reg. No.: 43/11/0014. S3 PENTASA ® 1 g Suppositories. Each suppository contains 1 g mesalazine. Reg. No.: A40/11/0374. S3 PENTASA ® 500 mg Tablet. Each tablet contains 500 mg mesalazine. Reg. No.: 33/11/0088. S3 PENTASA ® 1 g ENEMA. Each 100 ml rectal suspension contains 1 g mesalazine. Reg. No.: 44/11/0888. NAME AND BUSINESS ADDRESS OF THE HOLDER OF THE CERTIFICATE OF REGISTRATION: FERRING (Pty.) Ltd. Route 21 Corporate Park, 6 Regency Drive, Irene Ext 30. Pretoria, South Africa. Tel: +27 12 345 6358 Fax: +27 12 345 1156. www.ferring.co.za. PENTASA, FERRING, and the FERRING logo are registered trademarks of Ferring B.V. For full prescribing information please refer to the package insert approved by the medicines regulatory authority. 2021/016 Date of preparation: April 2021 *Although the disposition from Pentasa ® is impaired in case of diarrhoea, the changes were not substantial, and the disposition remains rather favourable. References: 1. Hardy JG, Harvey WJ, Sparrow RA, et al. Localization of drug release sites from an oral sustained-release formulation of 5-ASA (Pentasa ® ) in the gastrointestinal tract using gamma scintigraphy. J Clin Pharmacol. 1993;33:712-718. 2. Wilding IR. A scintigraphic study to evaluate what happens to Pentasa ® and Asacol ® in the human gut. Practical Gastroenterology. Suppl to November 1999:1-8. 3. Rijk MCM, van Schaik A, Van Tongeren JHM. Disposition of mesalazine from mesalazine-delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea. Scand J Gastroenterol 1992;27(10):863-868. 4. Christensen LA, Fallingborg J, Abildgaard K, et al. Topical and systemic availability of 5-aminosalicylate: comparisons of three controlled release preparations in man. Aliment Pharmacol Ther. 1990;4:523-533. PENTASA ® prolonged release granules Mesalazine is released throughout the GI tract? YES 1,2 Release of mesalazine at all pH values in the GI tract? YES 1 Does diarrhoea affect the release of mesalazine? * YES 3 Any peak plasma concentrations of mesalazine? 7 NO 4 May be taken with or without food? YES 1,2 BENEFITS OF PENTASA ® ORAL FORMULATIONS Be GUTsi Take Control B e PENTASA ’s different dosage forms & strengths allow you to choose the best fit for your patient. Monitor your symptoms closely and call your health care professional if symptoms worsen • Disease appears to be under control HELPING PEOPLE LIVE BET o download and use the IBD Health Diary app from Ferring e IBD Health app from Ferring CONTROL HOW APP FEATURE • Go to Google Play or the App Store • Search for the IBD Health Diary • Download the app to your phone or tablet • Fill in your personal details • Explore the features R n it's time for your xt doctor's visit PERSONAL HEALTH DIARY REPORT Automated report will be generated when a date range is selected. You have an option to e-mail the report to your health care professional with just one tap fi t i Overview Scheduler Personal Health Report Knowledge Base Answer pre-selected questions about your symptoms and get a colour-coded indication of your disease status • Contact your health care professional for advice SCAN QR CODE AT THE BOTTOM OF THE PAGE TO ACCESS APP APPLE QR CODE GOOGLE QR CODE th Diary is another innovation by Ferring. oach in empowering patients! Improving outcomes in the palm of your hands. Corporate Park, 6 Regency Drive, Irene Ext 30, Pretoria, South Africa. Tel: +27 12 345 6358. Fax: +27 12 345 1156. www.ferring.co.za. FERRING, and the ed trademarks of Ferring B.V. 2019/089 Date of preparation: November 2019. Monitor your symptoms closely and call your health care professional if symptoms worsen • Disease appears to be under control HELPING PEOPLE LIVE BETT download and use the IBD Health Diary ap from Ferring IBD Health pp from Ferring CONTROL HOW AP FEATURES • Go t Google Play or the App Store • Search for the IBD Health Diary • Download the app to your phone or tablet • Fill in your personal details • Explore the features it's time for your doctor's visit PERSONAL HEALTH DIARY REPORT Automated report will be generated when a date range is selected. You have an option to e-mail the report to your health care professional with just one tap K No fin the inf Overview Scheduler Personal Health Di Report Knowledge Base Answer pre-s lected questions about your symptoms and get a col ur-coded indication of your disease status • Contact your health care professional for advice SCAN QR CODE AT THE BOTTOM OF THE PAGE TO ACCESS APP APPLE QR CODE GOOGLE QR CODE h Diary is another in ovation by Ferring. ch in empowering patients! Improving outcomes in the palm of your hands. rpo ate Park, 6 Regency Drive, Irene Ext 30, Pretoria, South Africa. Tel: +27 12 345 6358. Fax: +27 12 345 1156. www.ferring.co.za. FERRING, and the trademarks of Ferring B.V. 2019/089 Date of pre aration: November 2019. Monitor your symptoms closely and c ll y our health care professional if sympt ms w rsen • Disease appears to be under contro HELPING PEOPLE LIVE BETT to download and use the IBD Health Diary app from Ferring he IBD Health app from Ferring E CONTROL HOW APP FEATURES • Go to G ogle Play or the App Store • Search fo the IBD H alth Diary • Download the app o your phone or tablet • Fill in your personal etails • Explore the features ER en it's time for your xt doctor's visit PERSONAL HEALTH DIAR REPORT Automated report will be generated when a date range is selected. You have an option to e-mail the report to your health care professional with just one tap K N fin th in Overview Scheduler Personal Health D Report Knowledge Base Answer pre-selected questions about y our symptoms and get a colour-coded ind ication of your disease status • Contact your health care profession al for advice SCAN QR CODE AT THE BO TOM OF HE PAGE TO AC ESS APP APPLE QR CODE GOOGLE QR CODE lth Diary is another innovation by Ferring. oach in empowering patients! Improvi g outcomes in the palm of y ur ha ds. 1 Corporate Park, 6 Regency Drive, Irene Ext 30, Pretoria, South Africa. Tel: +27 12 345 6358. ax: +27 12 345 1156. www.ferring.co.za ERRING, and the ed trademarks of Ferring B.V. 2019/089 Date of preparation: November 2019. Google QR code M nitor your symptoms close y and ca l your health care professional if sy ptoms worsen • Di ase appears to be under c ntrol HELPING PEOPLE LIVE BE to download and use the IBD Health Diary a p from Fe ring the IBD Health a p from Ferring E CONTROL HOW APP FEATURE • Go t G og e Play or the A p Store • Search for the IBD ealth Diary • Download the a p to your phone or tablet • Fill in your personal details • Explor the feature ER en it's time for your ext doctor' visit PERSONAL HEALTH DIARY REPORT Automated report will be generated when a date range i s lected. You have an pti n to e-mail the repor to your health care professional with just one tap O erview Scheduler Personal Health Report Knowl dge Bas Answer pre-s lected questions about your symptoms and get a c lour-coded ind cation f your di ase status • Contact your health care professional for advice SCAN QR ODE A THE BOTTO OF THE PAGE TO A CESS APP APPLE QR CODE OOGLE QR CODE lth Diary is another i novation by Fe ring. roach in empowering patients! Improving outcomes in the palm of your hands. 21 Corpor te Park, 6 R gency D ive, Ir ne Ext 30, Pretoria, South Africa. T l: +27 12 345 6358. Fax: +27 12 345 1156. w w.ferring.co.za. FERRING, and th ered trademarks of Ferring B.V. 2019/089 Date of prep ration: November 2019. M nitor your symptoms closel and cal your health care professional if symptoms worsen • Dise se ap ears to be un er contr l HELPING PEOPLE LIVE BE o downloa and use the IB ealth Di ry from Fe ing e IBD ealth a p from Fe ing O A P A U ES Go to G ogle Play or the A p Store e rch f r the IBD Health Diary • Download the a p to your phone or tablet Fil in your personal etails xplore the features R n it's time f r your t doctor's v sit P O L LT I EP Automated rep rt wil be generated when a date range is s lected. ou have n option to e-mail the rep rt to your health care profes ional with just ne tap fi th in Overview che uler Personal Health e rt n wled e Base Answer pre-s lected questions about your symptoms and get a colour-co ed indication of your dise se sta us • Contact your health care professional for advice S AN QR CO E AT THE BOTTOM OF THE PAGE TO A ESS A P A PLE QR CODE G OGLE QR CODE h iary is another i novation by Fe ring. ach in empowering patients! Improving outcomes in th palm of your hands. Corporate Park, 6 R gency Drive, Irene Ext 30, Pretoria, South Africa. Tel: +27 12 345 6358. F x: +27 12 345 115 . www.ferring.co.za FERRING, and the d trademarks of Fer ing B.V. 2019/089 Date of pre ration: November 2019. Monitor your symptoms closely and call your health care professional if sympt m w rsen • Disease appears to be under con tro HELPING PEOPLE LIVE BET E o download and use the IBD Health Diary ap rom Fer ing e IBD Health ap from Ferring E CONTROL HOW APP FEATURES • Go to Go gle Play or the Ap St re • Search fo the IB H alth iary • Downl ad the ap o your phone r tablet • Fill in your per onal etail • Explore the features ER n it's time for your t doctor's vis t PERSONAL H ALTH DIAR R PORT Automated report will be generated when a date range is sel cted. You have an option to e-mail the report o your health care professional with just one tap KN No fin the info Overview Scheduler Personal Health Dia Report Knowledge Base Answer pre-selected questions about y ur symptoms and get a col ur-coded ind t on of your disease status • Contact your health care professio n l for advice SCAN QR ODE AT THE BO TOM OF HE PAGE O AC ESS APP AP LE QR CODE GO GLE QR CODE th Diary is another in ovation by Fer ing. oach in empowering patients! Improving outc mes in the palm of y ur hands. Corporate Park, 6 Reg ncy Drive, Iren Ext 30, Pretoria, South Africa. Tel: +27 12 345 6358. ax: +27 12 345 1156. www.ferring.co.za ERRING, and the trademarks of Ferring B.V. 2019/089 Date of prepar tion: November 2019. Ap le QR code PENTASA ® SACHETS Ulcerative Colitis & Crohn’s Disease PENTASA ® 1 g SUPPOSITORIES Ulcerative Proctitis PENTASA ® 1 g ENEMA Ulcerative Procto ig oiditis & Left-sided C litis The Be GUTsi campaign & IBD Health Diary are the latest innovations by Ferring. A NEW approach in empowering patients! Improving outcomes in the palm of your hands. To remission and beyond. PENTASA ® 500 mg TABLETS Ulcerative Colitis